New WHO histologic classification predicts prognosis of thymic epithelial tumors

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New WHO histologic classification predicts prognosis of thymic epithelial tumors: a clinicopathologic study of 200 thymoma cases from China.

BACKGROUND In 1999, a World Health Organization (WHO) committee published histologic criteria for distinct thymoma entities (labeled as Type A, AB, B1, B2, B3 thymomas) and for the heterogeneous group of thymic carcinomas, collectively called Type C thymomas. Whether WHO-defined histologic thymoma subtypes are of independent prognostic relevance has yet to be proved. METHODS Two hundred thymo...

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STAT3 expression correlates with prognosis of thymic epithelial tumors

BACKGROUND More and more evidences demonstrate the significance of Signal transducers and activators of transcription 3(STAT3) in oncogenesis and tumor development. However, little systematic researches have been reported on the correlation between STAT3 and thymic epithelial tumor (TET). METHODS Expression of STAT3 protein in 80 thymic epithelial tumors was detected by immunohistochemistry (...

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Relationship Between CT Manifestations of Thymic Epithelial Tumors and the WHO Pathological Classification

Thymic epithelial tumors account for 15-21.7% of mediastinal tumors and 47% of anterior mediastinal tumors (Chen et al., 2002; Engels and Pfeiffer, 2003). Until 2004, there was a wide range of pathological classifications for thymic tumors (Travis et al., 2004; Okumura et al., 2008). The World Health Organization (WHO) updated the pathological classification in 2004, and thymic tumors are now c...

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Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients

Background: Thymomas are rare epithelial tumors arising from thymus gland. This study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. Methods: Forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital duri...

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Outcome of surgical treatment for recurrent thymic epithelial tumors with reference to world health organization histologic classification system.

BACKGROUND AND OBJECTIVES The aim of this study was to clarify the significance of surgical treatment for recurrent thymic epithelial tumors with reference to the World Health Organization (WHO) histological classification system. PATIENTS Among 67 patients with tumor recurrence, 22 underwent a re-resection. There were 1 patient with a type AB tumor, 5 with type B1 tumors, 10 with type B2 tum...

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ژورنال

عنوان ژورنال: Cancer

سال: 2002

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.10665